SPM12

Preprocessing resting-state fMRI

SPM standard pipeline

You can download the batch matlab script here. The preprocessing pipeline entails:

• Realignement & Slice timing

• Co-registration of the T1w image to the mean image created by the realignement procedure

• Segmentation

• Normalization

• Smoothing (6mm FWHM Gaussian kernel)

ART

Motion parameters from the realignment are evaluated with ART (Artifact Detection Tool; Massachusetts Institute of Technology) to detect outlying volumes:

• Interscan movement threshold of 3 mm in translation, 0.02 rad in rotation

• Global interscan signal intensity of 3 SD relative to the session mean.

• Individuals with 10% of more outlying volumes can be considered outliers